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2025 NFL Draft No. 1 pick odds: Shedeur Sanders emerges as early favorite



With this year’s festivities in Detroit coming to a close, oddsmakers are already weighing in on the 2025 NFL Draft class. 

And a big name has already established himself as an early favorite to go No. 1 overall. 

Colorado quarterback Shedeur Sanders, son of NFL Hall of Famer and Buffaloes head coach Deion Sanders, is a heavy favorite to be the first name off the board next April with +100 odds at DraftKings Sportsbook

After transferring from Jackson State before last season, Sanders enjoyed a breakout season in Boulder, throwing for 3,230 yards with 27 touchdowns and just three interceptions. 

But Colorado finished a disappointing 4-8 after shocking the college football world with a 3-0 start. 

A couple of other college signal-callers form a clear top three on DraftKings’ oddsboard. 

2025 NFL Draft No. 1 overall pick odds

Player Odds
Shedeur Sanders +100
Quinn Ewers +300
Carson Beck +300
Drew Allar +850
Jalen Milroe +950
Jaxson Dart 12/1
Cam Ward 15/1
Mykel Williams 18/1
Patrick Payton 18/1
Odds provided by DraftKings Sportsbook

Quarterback Shedeur Sanders #2 of the Colorado Buffaloes runs out of the pocket against the Arizona Wildcats in the first quarter at Folsom Field on Nov. 11, 2023 in Boulder, Co. Getty Images

Texas quarterback Quinn Ewers and Georgia quarterback Carson Beck both own +300 odds, suggesting that either player could easily leapfrog Sanders with a big season. 

Four more quarterbacks – Penn State’s Drew Allar (+850), Alabama’s Jalen Milroe (+950), Ole Miss’ Jaxson Dart (+1200) and Miami’s Cam Ward (+1500) – round out the top seven, before we get to the first defensive player in the conversation, Georgia edge rusher Mykel Williams (+1800). 

Sanders’ teammate, the two-way star Travis Hunter, is also a first-overall pick contender, according to oddsmakers. 

Hunter, who played corner and wide receiver for the Buffaloes last season, has the 14th-best odds (+2200) to be selected No. 1. 

Betting on the NFL?

No matter how this college football season plays out, it’s looking as if next year’s first-overall pick competition will be much different than the 2024 draft. 

When odds opened this time last year, Caleb Williams was already a massive -550 favorite to be the first pick, which ended up ringing true when the Bears made him their franchise quarterback Thursday. 

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